Chapter 8 Learning Objectives:
- Be able to define: syn addition, anti addition, electrophilic
addition, halonium ion, chloronium ion, bromonium ion.
- Be able to state Markovnikov’s Rule. Explain the chemical principles
responsible for the predicted regioselectivity.
- Be able to classify the following as Markovnikov Addition or
Anti-Mrkovnikov addition reagents: HX, HBr with H2O2,
H2O with H2SO4,
oxymercuration-demercuration, hydroboration-oxidation.
- Be able to predict the major product (including regiochemistry and
stereochemistry) for the electrophilic addition reagents: HX, HBr with
H2O2, H2O with H2SO4,
oxymercuration-demercuration, hydroboration-oxidation, catalytic
hydrogenation, X2, X2 with nucleophile, glycol
formation, oxidative cleavage reactions.
- Be able to draw a mechanism using curvy arrows for each of the following
reactions: HX, HBr with H2O2, H2O with H2SO4,
oxymercuration-demercuration, hydroboration-oxidation, catalytic
hydrogenation, X2, X2 with nucleophile, glycol
formation.
- Be able to propose the synthetic steps necessary to synthesis a target
molecule given one or more starting compounds.