Chapter 5 Learning Objectives:
- Be able to define and give an example: stereochemistry,
superimposable, chiral, achiral, chiral carbon, asymmetric carbon,
stereoisomers, enantiomers, diastereomers, chirality, optical isomers,
plane-polarized light, optical purity, enantiomeric excess, polarimeter,
meso compound, racemic mixture, specific rotation, dextrorotatory,
levorotatory, resolution, Cahn-Ingold-Prelog convention.
- Be able to draw the mirror image of a given molecule and determine whether
the two structures are enantiomers or the same compound.
- Be able to label any asymmetric carbon atoms (chiral carbons) and
stereocenters within a given molecule.
- Be able to classify a molecule as chiral or achiral.
- Be able to use the Cahn-Ingold-Prelog convention to assign R
or S configuration to chiral centers.
- Be able to name a given chiral compound including the R
and S configuration for any chiral center in the molecule.
- Be able to draw a chiral compound including the R
and S configuration for any chiral center in the molecule given a
name.
- Be able to determine if a molecule is optically active.
- Be able to describe a polarimeter.
- Be able to determine whether two given structures are enantiomers,
diastereomers, same compounds, or conformational isomers.
- Be able to determine whether two given structures are meso
compounds.
- Know the similarities and differences in physical properties of
enantiomers.
- Know the similarities and differences in physical properties of
diastereomers.
- Be able to determine the enantiomeric excess and optical purity of a
sample given the sample optical rotation and the specific rotation of an
optically pure sample.
- Be able to write the steps needed to resolve a racemic mixture of
carboxlic acids.
- Be able to write the steps needed to resolve a racemic mixture of
alcohols.