Research Interests
Dr. Richard Singiser
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My research revolves around two different themes, designing novel chemistry and biochemistry teaching laboratories, and the cytoskeletal protein talin.
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Talin
My work on biochemistry teaching labs involves applying concepts in biochemistry to unique laboratory experiences for undergraduate students. A few of the labs that are currently in preparation involve amino acid identification, protein purification, protein separation, protein identification, and enzyme kinetics. Nucleic acid identification, purification, amplification, and separation labs are also being developed. Labs involving both lipids and carbohydrate chemistry are being prepared as well. Research in this area will provide the interested student with the opportunity to learn new laboratory skills and to begin developing independent scientific investigation skills.
My research on the cytoskeletal protein talin combines multiple areas of the biological sciences to address questions related to cell function and disease. Talin is a very large protein that links the extracellular matrix to the actin cytoskeleton. Talin provides a framework for other proteins to bind and assist in the formation of large, multi-protein complexes called focal adhesions. Dysregulation of focal adhesions can lead to a variety of diseases including cancer metastasis. Research on talin applies many laboratory techniques from multiple disciplines of science, including biochemistry, cell biology, and molecular biology. The motivated student doing research on this project will have the opportunity to do integrative research applying skills they have learned in multiple classes.
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This page was last updated on 01/08/2009