CLAYTON STATE UNIVERSITY

 

BIOL 4450 - Immunology

Course Syllabus – Fall 2009

 

_____________________________________________________________

Individuals with disabilities who need to request accommodations should contact the Disability Services Coordinator, Student Center 214, 978-466-5445, disabilityservices@mail.clayton.edu.

 

Course Description

 

BIOL 4450 (CRN 87779) - Immunology - 3.0 semester credit hours.

This course will include a comprehensive overview of the immune system and its functions within the context of cell to cell interaction and communication.

 

Prerequisites:

Biol 3200 with a minimum US grade of D

 

Notebook Computer Requirement:

Each CSU student is required to have ready access throughout the semester to a notebook computer that meets faculty-approved hardware and software requirements for the student's academic program. Students will sign a statement attesting to such access.  For further information on CSU's Official Notebook Computer Policy, please go to

http://itpchoice.clayton.edu/policy.htm.

 

Computer Skill Prerequisites:

•   Able to use the WindowsTM operating system.

•   Able to use the Microsoft WordTM word processing program.

•   Able to send and receive e-mail using the OutlookTM or Outlook ExpressTM program.

•   Able to use a Web browser.

 

In-class Use of Student Notebook Computers:

Student notebook computers will be used in this class.   We may have some in class projects when you will be required to bring your computer to class.  In addition, computers will be required to access course materials, to communicate with your instructor and to access science articles in the literature relating to immunology.  At other times, you will not be allowed to use your computers (see below).

 

Course Objectives:

• To develop an awareness of experimental design and scientific method.

• To acquire a working vocabulary in immunology.

• To understand and discuss the development and evolution of the immune system.

• To gain an understanding of the key cells involved in the immune response.

• To understand the relationship of antigen, antibody, and antigen receptor molecules.

·  To gain a basic knowledge of the generation of diversity involved in antibodies and T-cell antigen receptors.

·  To distinguish and understand the humoral and cell-mediated immune responses.

·  To gain a basic understanding of the current theories on the regulation of the immune response.

·  To discuss the host's ability to mount an immune response to invading microorganisms

·  To gain a basic understanding of tumor immunology, immunodeficiency, autoimmunity, hypersensitivities, and transplantation rejection.

General education outcomes:

The following links provide tabular descriptions of the communications outcome and the critical thinking outcome components  (see PHYS 1111 in the tables):

        Critical thinking outcomes components

Student Learning Outcomes:

·        Knowledge of the basic principles of major fields of biology particularly as they relate to the immune system.

·        Mastery of a broad range of basic lab skills applicable to biology.

·        Knowledge of physical science, mathematics, and statistics required to support an understanding of biology.

·        Ability to communicate orally and in writing in a clear, concise manner.

·        Ability to collect, evaluate and interpret scientific data, and employ critical thinking to solve problems in biological science and supporting fields.

·        Ability to function effectively on team-oriented projects.

·        Appreciation for the impact of biological science on the environment and society.

 

•   Teacher Education Standards:

The content of this course syllabus correlates to education standards  established by national and state education governing agencies, accrediting agencies and learned society/ professional education  associations.  Please refer to the course correlation matrices located at the following web site:

 

http://a-s.clayton.edu/teachered/Standards%20and%20Outcomes.htm

 

 

Instructor Information:

 

Section 1

Dr. Fran Norflus (CRN 87779)

Office: Faculty Hall, Room A23B

Phone: (678) 466-4852

email: Fnorflus@clayton.edu

Internet address: http://a-s.clayton.edu/fnorflus/

Office Hours:

Tuesdays, 11:15 AM – 1:00 PM & 2:00 – 4:30 PM, Thursdays, 11:15 AM  - 12:00 PM

Office hours will be held in room A23B or C28

Thursdays, 8:00 – 9:00 PM, online office hours

 

Class Meetings:

Days: Tuesdays and Thursdays

Times: 9:50 - 11:05 AM

Room: B13

Instructor: Dr. Norflus

 

Textbook Information:

Required:

Kindt, Goldsby and Osborne, Kuby, Immunology, sixth edition, W.H. Freeman and Company, 2007

Recommended:
Writing papers in the biological sciences, 4th edition, Victoria E. McMillan.  2006.  Bedford/St. Martin's.  New York.

 

 

Text Coverage:

Chapters to be covered: 1-9, 19 and 22.  There will also be many outside articles to read which will either be copied by the instructor, posted on the class web site or in Georgia Vista.

 

Evaluation:

 

ITEM

POINTS

% OF FINAL GRADE

Exam 1

100 points

18.2 %

Exam 2

100 points

18.2 %

Civic engagement and disease project

150 points

27.3 %

Experimental system

50 points

9.1 %

Speaker

50 points

9.1 %

Cumulative final exam

100 points

18.2 %

 

There will be 2 hour long examinations in this class.  There will also be a cumulative final examination.  Each will be worth 100 points.

 

There will also be 3 projects that you will need to do.

 

1.     You will need to participate in a civic engagement and disease project relating to immunology.

a.      You will need to volunteer, raise money and/or participate in a walk for a particular organization.  For example, you may participate in a walk for diabetes or breast cancer.  More specifics will be described in a different document but you will need to provide proof showing what you did.  One purpose for this activity is for you to gain appreciation for patients that have a particular disease (25 points).

b.     You will need to keep a notebook that you can work on throughout the semester.  You will need to pick a specific CANCER that you HYPOTHETICALLY have been diagnosed with. This can be different from the disease that you selected for part a. You will need to include the following information. (75 points)

1.     What is your cancer?

2.     How are cancer cells different from non cancer cells?

3.     What is the diagnosis?  What are your symptoms? Don’t just state you have cancer.  Be specific.

4.      How do you feel about the diagnosis and symptoms?

5.     Who would you tell?

6.     Would you tell your insurance company (that really means who you have them pay for your treatment)?  What effect(s) might that have?

7.     Do you think there is a link between your lifestyle and your disease?  Or, is there a genetic link?

8.     What are some treatment options?

9.     Which treatment will you choose? How will you cope with the stress that this causes?  For example, you may need to spend a lot of time at the hospital.

10.      What are some side effects, problems with these treatment options?

11.      State if your treatment worked or not.

12.      If it was successful. Why do you think it worked?

13.      What follow up care do you need?

14.      If the treatment was not successful, what are some other options?

15.      Would you get involved in clinical trials?  Will your insurance company pay for it?

16.      What is your 5 year survival rate?

17.      How do you feel about your final prognosis?

18.      What are your plans for the future if you are given a poor prognosis?

19.      Your notebook will be collected various times during the semester.

c.      You will need to give a 10 minute presentation about your experiences doing this project.  Explain what your civic engagement project was and what you learned and did for your disease project (25 points).  Other students may not have their computers out or phones out or on during these presentations.

d.     You will need to make a 1-2 page outline on your disease project and write 3 questions on your disease that could be used for an exam.  More specifics on the disease will be posted later in the semester (25 points)

 

You will need to get into groups of 2-3 to perform this project.  Each member of the group will get the same grade.  However, if a member of the group does not perform part a of the project, his/her grade will differ.  In addition, only 1 (or 2 members) of the group needs to make the presentation for part c. Each member of the class needs to be present on the day of the presentation.  If a member of the group is not present on this day, he/she will get a grade of 0.  If they have a valid excuse for missing part c, then they will need to give their own presentation to the class at another time.

 

The grading for parts c and d of the project will be based on the clarity of the presentation, organization, write-up for students, write-up for instructor and ability to answer questions.  More specifics on the grading will be given later in the semester.

 

2.     There is also an experimental systems project.  There are many different techniques that can be used to study various aspects of immunology.  These are described in chapters 6 and 22.  You will need to work in a group for this project (which can be different from the group for the civic engagement project).  You will need to do the following.

a.      You will be given a technique that you will need to research.

b.     Make up a handout explaining this technique  (12.5 points)

c.      Make a PowerPoint explaining the technique (you will need to get pictures from the Internet or you can take pictures of equipment that we have in the laboratory) (12.5 points)

d. Present the PowerPoint to the class (12.5 points). Other students may not have their computers out or phones out or on during these presentations.

e. Write 3 potential exam questions and answers. You are expected to write test questions at the level of a junior or senior college student.  (12.5 points)

 

You will need to get into groups of 2-3 to perform this project.  Each member of the group will get the same grade.  However, only 1 (or 2 members) of the group needs to make the presentation for part c but each member of the class needs to be present on the day of the presentation.  If a member of the group is not present on this day, he/she will get a grade of 0 on the entire project.  If they have a valid excuse for missing the presentation, then they will need to give their own presentation to the class at another time.  Their grade for parts b, c and e will be the same as their group but their grade on part d may be different.

 

We will not be able to go through all of the different techniques in the class.  For the exam, I will give you a choice of techniques to discuss. If you are working with the same group for the diseased project and the experimental systems project, different members of the group will need to give the presentation.

 

3.     Speaker project

 

We will have 2 speakers during this class.  You will need to come to class and listen to the speaker.  You will then write a 1-2 page summary of the speaker in OUTLINE form (25 points).  If you write an essay, you will receive a 0 on this assignment.  You will also write 3 potential test questions with answers (25 points).  You will be graded on these but they will not be on the exam.   You are expected to write test questions at the level of a junior or senior college student.  You will work on this project individually.  You may only complete this assignment if you are on class that day.

 

You will need to take notes with paper and pen on this day.  You may not use your computer.  It is distracting to the speaker.   Do not take your computer out.  I do not want to ask you to put it away.

 

You may not have your cell phone ring or vibrate during the presentation or you will get a grade of 0.

 

This is an assignment that you will need to do on your own.  You may not record the speaker or contact them after the talk to ask for their presentation.

If you have questions, then ask them during class.

 

Grading:

 

Your final grade will be determined as follows:

 

A, 90 - 100%

B, 80 - 89%

C, 70 - 79%

D, 60 - 69%

F, below 60%

 

Course Policies:

Students must abide by policies in the Clayton State University Student Handbook, and the Basic Undergraduate Student Responsibilities

University Attendance Policy

Students are expected to attend and participate in every class meeting. Instructors establish specific policies relating to absences in their courses and communicate these policies to the students through the course syllabi. Individual instructors, based upon the nature of the course, determine what effect excused and unexcused absences have in determining grades and upon students’ ability to remain enrolled in their courses. The university reserves the right to determine that excessive absences, whether justified or not, are sufficient cause for institutional withdrawals or failing grades.

 

Course attendance policy
Regular and punctual attendance is highly recommended.  We will be covering material in class that may not be found in the textbook.  Announcements concerning changes in test dates, and assignment due dates will be made during class.  If you must be absent due to illness or other unforeseeable event, you are still responsible for any and all information given during class.  This may include changes in test dates, assignment due dates, and the syllabus.  If the instructor gives out any handouts during a class that you missed, you must contact ANOTHER STUDENT to get this information.  The instructor will not be carrying around extra copies waiting for you to return to class.

Missed exams or assignments

Absences from EXAMS must be accompanied by a signed physician's or judge's excuse (there are no exceptions). Without an excuse provided within one week, a grade of zero points will be assigned for the missed exam.  You must provide an original copy of the excuse. If the student does have a valid excuse the final exam will be doubled to make up for the missed exam. If a student misses part of an exam, then those points will be doubled on the final exam and the student will only take part of the exam.  For example, if a student misses 50 points out of a 100 point exam, then the student will have half of the final exam count twice. So, if the student gets 35/50 on the test and 80 on the final, the two tests will be combined so that he/she has 35 + 120 points on the two tests combined.  A student may not miss more than one exam.   If the final exam has been missed, a makeup will be administered. 

If your disease project notebook is handed in late, 10% of the grade will be deducted for each day that it is late.  No assignments will be accepted after 3 days past the due date.

If your experimental systems project is handed in late, 10% of the grade will be deducted for each day that it is late.  No assignments will be accepted after 3 days past the due date.  If you have a valid excuse for missing the presentation for the experimental systems project, then you will need to give your own presentation to the class at another time.  If you do not have a valid excuse, you will receive a grade of 0 on this part of the project.

If one or members of your group is not participating in the project (as evidenced by the fact that the instructor is informed by other students), the instructor reserves the right to remove the student from the group who will then need to perform the project by his/herself.

If your speaker project assignment is handed in late, 10% of the grade will be deducted for each day that it is late.  No assignments will be accepted after 3 days past the due date.  You must be in class to complete this assignment.  If your cell phone rings or vibrates during this presentation, you will be given a grade of 0 on the assignment and you will not be allowed to do the assignment for any of the other speakers.  You will get a grade of 0 for the assignment.

Other policies

The final exam will be multiple choice.  You will need to bring a scantron.  If you do not write your answer on a scantron, I will deduct 10 points from your final exam grade.

Visitors (friends, children, etc.) are strictly prohibited from attending class without the permission of the instructor.

No smoking, eating or drinking is permitted at any time in the classroom.

Students may not use laptop computers for anything other than note taking during class.  Students using laptop computers for anything else (including, but not limited to, instant messaging, sending or receiving email, playing games, or surfing the internet) will be asked to leave the class.  Computers may not be used in class during any of the presentations.

Cell phone use during class is disrespectful and distracting to the instructor and other students.  Any student using their cell phone during class (ringing, talking, or sending/receiving text messages) will have the phone confiscated and must come see the me at the end of class to get it back. It is suggested you switch your phone to the off position before class begins.  If your phone rings or vibrates during either the faculty presentations or student presentations, the student will be given a grade of 0 on the assignment for the day (even if they are not presenting that day).

Behavior which disrupts the teaching–learning process during class activities will not tolerated.  While a variety of behaviors can be disruptive in a classroom setting, more serious examples include belligerent, abusive, profane, and/or threatening behavior.  A student who fails to respond to reasonable faculty direction regarding classroom behavior and/or behavior while participating in classroom activities may be dismissed from class.  A student who is dismissed is entitled to due process and will be afforded such rights as soon as possible following dismissal.  If found in violation of this policy, a student may be administratively withdrawn and may receive a grade of WF.  Please refer to http://a-s.clayton.edu/DisruptiveClassroomBehavior.htm for more information.

Exams will generally be given at the start of class.  You are expected to be in class at the beginning of the period.  It is very disruptive of your other students if you show up late.

No form of academic dishonesty will be tolerated in this class.  Any type of activity that is considered dishonest by reasonable standards may constitute academic misconduct. The most common forms of academic misconduct are cheating and plagiarism.  All instances of academic dishonesty will result in a MINIMUM penalty of a grade of zero for the work involved.  All instances of academic dishonesty will be reported to the Office of Student Life/Judicial Affairs.  Judicial procedures are described at http://adminservices.clayton.edu/judicial/.

Changes or additions to this syllabus, including reading, exam schedule, grading, and course policies can be made at the discretion of the instructor at any time.

 



Last update: 08/05/09